Doing research into health and the delivery of healthcare services is vitally important to the NHS because the outcomes can be used to influence the quality of services delivered to patients.
This means that patients are able to gain access to the best available treatments and services, which have been rigorously tested, as well as innovative and leading edge treatments that can significantly improve health outcomes.
In the Cardiac Surgery team, each of our consultants have specialist research interests. On this page we detail some of the recent research presentations and publications that have been made by the team.
Recent Multi-centre Studies that we contributed to
Percutaneous coronary angioplasty versus coronary artery bypass grafting in treatment of unprotected left main stenosis (NOBLE): a prospective, randomised, open-label, non-inferiority trial. Mäkikallio T, Holm NR, Lindsay M, Spence MS, Erglis A, Menown IB, Trovik T, Eskola M, Romppanen H, Kellerth T, Ravkilde J, Jensen LO, Kalinauskas G, Linder RB, Pentikainen M, Hervold A, Banning A, Zaman A, Cotton J, Eriksen E, Margus S, Sørensen HT, Nielsen PH, Niemelä M, Kervinen K, Lassen JF, Maeng M, Oldroyd K, Berg G, Walsh SJ, Hanratty CG, Kumsars I, Stradins P, Steigen TK, Fröbert O, Graham AN, Endresen PC, Corbascio M, Kajander O, Trivedi U, Hartikainen J, Anttila V, Hildick-Smith D, Thuesen L, Christiansen EH; NOBLE study investigators.Lancet. 2016 Dec 3;388(10061):2743-2752.
Recent Cardiac Surgery Publications from the Unit
Fibroelastoma of the mitral valve apparatus. Crean J, Clinton A, Afredi N, Dougherty M, Jeganathan R. J Card Surg. 2018 Aug;33(8):442-443.
Fibroelastoma of the aortic valve. McCanny A, Imran Hamid U, Carroll S, Jeganathan R. J Card Surg. 2017 Nov;32(11):698-699.
A pathway to earlier discharge following TAVI: Assessment of safety and resource utilization. Noad RL, Johnston N, McKinley A, Dougherty M, Nzewi OC, Jeganathan R, Manoharan G, Spence MS. Catheter Cardiovasc Interv. 2016 Jan 1;87(1):134-42.
Radial Multi-Site, Longitudinal Multi-Polar Epicardial Left Ventricular Pacing In Tricuspid Valve Disease. Lau EW, McEntee T, Ashfield KB, Graham AN. Ulster Med J. 2016 Sep;85(3):193-195.
An impressive fungal infection of a permanent pacing system. Beattie R, Nzewi OC, Wilson C. Eur Heart J. 2016 Oct 14;37(39):3060.
Incidence and outcome of re-entry injury in redo cardiac surgery: benefits of preoperative planning. Imran Hamid U, Digney R, Soo L, Leung S, Graham AN. Eur J Cardiothorac Surg. 2015 May;47(5):819-23.
Cardiac sarcoma causing mechanical tamponade: a radiological dilemma! Burnside N, Jeganathan R. Eur Heart J. 2015 Dec 21;36(48):3459.
Gigantic left atrium – can surgery reverse the downward spiral of cardiac cachexia?Beattie R, Johnston P, Jeganathan R. Ulster Med J. 2014 Sep;83(3):180-1.
Which is the best graft for the right coronary artery? Parissis H, Ramesh BC, Al-Alao B. Asian Cardiovasc Thorac Ann. 2014 Feb 18.
Sarcoidosis or acute coronary syndrome: Easily distinguishable? Marley WD, Booth K, Jeganathan R. Asian Cardiovasc Thorac Ann. 2014 Jun 4.
Nocturnal dyspnoea in a patient with previous nephrectomy. Daly MJ, Paul I, Jeganathan R, Johnston NG. Eur Heart J. 2014 Apr 8.
Carotid-Access Transcatheter Aortic Valve Replacement in a Patient with a Previous Mitral Valve Replacement. Daly MJ, Blair PH, Modine T, Donnelly PM, Jeganathan R, Manoharan G, Spence MS. J Card Surg. 2014 Mar 10.
Early experience of implantation of the new CoreValve(®) Evolut(™) in degenerated bioprosthetic aortic valves. Fairley SL, Jeganathan R, Manoharan G, Spence MS. Catheter Cardiovasc Interv. 2014 Feb 15;83(3):485-92.
Systolic anterior motion of mitral valve with calcified annulus in octogenarians. Parissis H, Hamid UI, Jeganathan R, Graham A. Asian Cardiovasc Thorac Ann. 2013 Aug;21(4):456-9.
Double patch repair for a double ventricular rupture. Sharma D, Manoharan G, Parissis H. Asian Cardiovasc Thorac Ann. 2013 Aug;21(4):470-2
An unexpected mortality following cardiac surgery: a post-mortem diagnosis of cardiac amyloidosis. Fitzmaurice GJ, Wishart V, Graham AN. Gen Thorac Cardiovasc Surg. 2013 Jul;61(7):417-21.
Ascending aorta thrombus: A diagnostic and treatment dilemma. Soo A, Marley D, McGrath-Soo L, Herron B, Parissis H. Asian Cardiovasc Thorac Ann. 2013 Oct 3;22(6):731-733.
Complete right ventricular obstruction caused by a giant cardiac myxoid sarcoma. Soo A, Molloy F, Herron B, Parissis H. Asian Cardiovasc Thorac Ann. 2013 Oct 3;22(5):611-613.
Translocation of dehisced aortic prosthesis to left ventricular outflow tract. Soo A, McGrath-Soo L, Parissis H. Asian Cardiovasc Thorac Ann. 2013 Aug;21(4):486.
Two questions on bilateral internal mammary artery usage. Parissis H, Chughtai Z, Soo A. Asian Cardiovasc Thorac Ann. 2013 Dec;21(6):751-5.
Depicting adverse events in cardiac theatre: the preliminary conception of the RECORD model. Parissis H, Mc Grath-Soo L, Al-Alao B, Soo A. J Cardiothorac Surg. 2013 Mar 19;8:51
Cardiac surgical patients are not the same. But who knows that: the patient, the cardiologist or the surgeon? Parissis H, Al-Alao B. Gen Thorac Cardiovasc Surg. 2013 Dec;61(12):685-93.
Rapid pannus formation after few months of obstructing aortic mechanical prosthesis. Al-Alao B, Simoniuk U, Heron B, Parissis H. Gen Thorac Cardiovasc Surg. 2013 Sep 25.
Ultrasound mapping of the long saphenous vein in coronary artery bypass graft surgery. Soo A, Noel D, Macgowan S. Interact Cardiovasc Thorac Surg. 2013 Jun;16(6):886-7.
Is there any further advantage of using more than one internal mammary artery? Literature review and analysis. Parissis H, Soo AW, Al-Alao B. Asian Cardiovasc Thorac Ann. 2013 Feb;21(1):101-13.
Alternative myocardial protection strategies are necessary in patients with intramural aortic course of anomalous coronary artery. Jadoon MA, Graham AN. BMJ Case Rep. 2012 Dec 18;2012.
Cytokine phenotype, genotype, and renal outcomes at cardiac surgery. McBride WT, Prasad PS, Armstrong M, Patterson C, Gilliland H, Drain A, Vuylsteke A, Latimer R, Khalil N, Evans A, Cambien F, Young I. Cytokine. 2013 Jan;61(1):275-84. doi: 10.1016/j.cyto.2012.10.008. Epub 2012 Nov 5.
Malignant primary cardiac tumours. Burnside N, MacGowan SW. Interact Cardiovasc Thorac Surg. 2012 Dec;15(6):1004-6
The hemodynamic and respiratory effects of continuous negative and control-mode cuirass ventilation in recently extubated cardiac surgery patients: Part 2. McBride WT, Ranaldi G, Dougherty MJ, Siciliano T, Trethowan B, Elliott P, Rice C, Scolletta S, Giomarelli P, Romano SM, Linton DM. J Cardiothorac Vasc Anesth. 2012 Oct;26(5):873-7. doi: 10.1053/j.jvca.2012.05.021. Epub 2012 Jul 13.
The hemodynamic and respiratory effects of cuirass ventilation in healthy volunteers: Part 1. McBride WT, Ranaldi G, Dougherty MJ, Siciliano T, Trethowan B, Elliott P, Rice C, Scolletta S, Giomarelli P, Romano SM, Linton DM. J Cardiothorac Vasc Anesth. 2012 Oct;26(5):868-72. doi: 10.1053/j.jvca.2012.05.009. Epub 2012 Jul 12.
A 15-cm aneurysm of the right coronary artery presenting as a pericardial cyst. Burnside N, Nzewi OC, Sidhu PS. Interact Cardiovasc Thorac Surg. 2012 Apr;14(4):483-4.
Successful management of membrane oxygenator failure during cardiopulmonary bypass–the importance of safety algorithm and simulation drills. Soo A, Booth K, Parissis H. J Extra Corpor Technol. 2012 Jun;44(2):78-80.
Ventricular assist device therapy in post-cardiotomy cardiogenic shock: historical outcomes and current trends. Nasir A, Bonde P, Graham AN. Interact Cardiovasc Thorac Surg. 2012 May;14(5):585-7.
Accidental transection of a radial artery cannula. Imran Hamid U, Collins A, McConkey C, Sidhu P. BMJ Case Rep. 2012 Sep 3;2012.
Intra-aortic balloon pump (ΙΑΒΡ): from the old trends and studies to the current “extended” indications of its use. Parissis H, Soo A, Al-Alao B. J Cardiothorac Surg. 2012 Dec 11;7:128.
Transthoracic intra-aortic balloon pump removal without repeat sternotomy. Soo AW, Parissis H. Asian Cardiovasc Thorac Ann. 2012 Oct;20(5):623-4.
Williams syndrome in an adult. McKenna AJ, Craig B, Graham AN. J Card Surg. 2010 May;25(3):339-42.
Have improvements in myocardial protection influenced a surgeon’s choice of coronary artery bypass surgery? Jeganathan R, Campalani G. Interact Cardiovasc Thorac Surg. 2010 Jun;10(6):855-8.
Transcaval migration of an acupuncture needle from the abdominal cavity to the heart. Neely D, Jeganathan R, Campalani G. J Card Surg. 2010 Nov;25(6):654-6.
Benefits of the preemptive intra-aortic balloon pump: an audit of practice in a regional cardiothoracic center. Nwaejike N, Campalani G, Gladstone D, Nzewi OC. Heart Surg Forum. 2009 Apr;12(2):E70-4.
Kommerell’s diverticulum, risk factor for aortic dissection. Nasir A, Jadoon M, Ellis PK, Graham AN. J Card Surg. 2009 Jul-Aug;24(4):463.
Stroke due to a cardiac myxoma. Al-Shahi Salman R, Northridge D, Graham AN, Grant R. BMJ Case Rep. 2009;2009. pii: bcr09.2008.0875
Some Recent Presentations at Scientific Meetings from the Unit
Post Cardiotomy Open Chest Management (PCOCM) – Is it Justifiable? N Haughey, K Booth, H Parissis – Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting, Edinburgh 2014
Current Demand for Surgery for Rheumatic Heart Disease in Northern Ireland U.Imran Hamid, A. Graham Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting Edinburgh 2014 http://www.scts.org/_userfiles/pages/file/Annual%20Meetings/SCTS%2014%20Prog%20Final%20Web%20res.pdf
Retrograde Autologous Prime: Is there an association between (sic) improved haemoglobin content during adult cardiac surgery? K Booth, N Haughey, R Jeganathan October 2013, Irish Cardiac Society, Oral Presentation
Incidence and outcome of re-entry injury in redo cardiac surgery U. Imran Hamid, A. Graham Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting 2013 http://abstracts.webges.com/itinerary/itinerary.php?i=1&abstract=348&keyword=IMRAN%20HAMID
Chronic ACE inhibition and renal function after elective cardiac surgery. Joseph J, McLean G, Shah S K, Bill KM, Khalil N, Gilliland H, Dougherty M, McBride WT. Association of Cardiothoracic Anaesthetists Meeting 2013 http://www.acta.org.uk/abstracts/abstract.asp?a=JAJACOSO198901JOPUIR11222013_53
The change of patient profile in non-elective coronary artery bypass surgery since the introduction of a primary percutaneous intervention service.
Beattie R, Wilson C, Graham A. Irish Cardiac Society Annual Meeting 2012